Researchers have unveiled genetically engineered mice that can run farther and longer than their naturally bred brethren, bringing the “genetic doping” of elite athletes a small step closer to reality.
The creation of the so-called marathon mice, announced in San Francisco, follows earlier genetic engineering work that created “Schwarzenegger mice”, rodents that bulked up after getting injected with muscle-building genes.
Scotsman article
The creation of the so-called marathon mice, announced in San Francisco, follows earlier genetic engineering work that created “Schwarzenegger mice”, rodents that bulked up after getting injected with muscle-building genes.
Athletes, sure. That's who we're wanting to modify. Yeah, that's right.
(DARPA's Creepy Bioengineering Program)
“This is a real breakthrough in our understanding of exercise and diet and their effects on obesity,” said lead researcher Ronald Evans of the Salk Institute in San Diego. “The practical use of this discovery is the implication in controlling weight.”
Health, sure. That's what we're looking at. Yeah, that's it.
"By changing the way skeletal muscles respond to low-oxygen levels, we've developed muscles that appear to be superiorly adapted or trained for long bouts of . . . aerobic exercise," Johnson said.
The gains in the UCSD study were temporary and came at a price, however. After four days of exercise tests, the genetically engineered mice endured much more muscle damage than normal mice, and they could no longer run or swim as much as their unaltered counterparts.
Sign on San Diego article
The gains in the UCSD study were temporary and came at a price, however. After four days of exercise tests, the genetically engineered mice endured much more muscle damage than normal mice, and they could no longer run or swim as much as their unaltered counterparts.
Oops.
In Evans' study [Ronald Evans, lead researcher in the Salk study], no adverse side effects were found in the engineered mice.
I've heard that before.
Besides Johnson and Mason, other UCSD scientists who contributed to the study included Richard Howlett, Matthew Kim, Mark Olfert, Michael Hogan, Wayne McNulty and Peter Wagner. Reed Hickey and Fran Giordano from the Yale University medical school and C. Ronald Kahn from the Harvard University medical school were also coauthors of the study, which was paid for by the National Institutes of Health.
Yale. Hmmmmm......
....but hey, do what you want....you will anyway.
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